Comparative evaluation of the effectiveness of Stevia extract used as powder versus Amoxicillin trihydrate powder in surgical extraction of mandibular third molar among 18-45-year-old adults - A split mouth Randomized controlled trial.â€

This is a split mouth randomized controlled trial to compare and evaluate the antimicrobial activity of stevia extract powder and amoxicillin trihydrate powder after surgical extraction of mandibular third molar extraction in an adult population 18 to 45 years group. The sample size was calculated as 40 patients. the sample size will be divided randomly into 2 groups consisting of 40 patients in each group using computer generated random numbers. Informed consent will be taken from the patient. The study group will consist of patients recieving stevia extract powder topically in the extraction socket followed by placement of abgel and suturing of the wound. the control group will consist of patients where administration of amoxicillin trihydrate powder topically in the extraction socket followed by abgel placement and suturing will be done. The postoperative outcomes to be assessed  are presence or absence of erythema, suppuration, pain, edema, Wound dehiscence, WBC counts, mouth opening and facial measurements. These outcomes will be recorder in a proforma for each patient.