跳至主要内容
临床试验/NCT05164380
NCT05164380已完成不适用

Picture Naming in the Context of Image Type and Response Variety in People With and Without Aphasia

Simone Hemm-Ode19 个研究点 分布在 1 个国家目标入组 66 人开始时间: 2019年4月29日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
66
试验地点
19
主要终点
Naming correctness

研究概览

简要总结

The observational study aims to investigate the effect of two factors that influence the ease with which aphasic and healthy participants name visual stimuli. The main factors investigated here are the image type of the visual stimulus (drawing or photographic image) and the response variety (standard language vs dialect). The hypothesis is formulated as follows: The image type of the visual stimulus (drawing or photographic image) and the response variety (standard language or dialect) will have an effect on naming correctness and/or naming latencies in people with aphasia within the picture naming test.

The experiment was as follows: Persons with aphasia and healthy participants were presented with objects and verbs depicted as photographs or illustrations on a tablet. All participants were asked to name the depicted term in two different language varieties as correctly and as fast as possible. Answers were recorded synchronously. No feedback should be given to the participants (=no therapy). The results of picture naming were not analyzed patient-specifically in relation to their condition or therapy. Naming performance was collected as a momentary data set in order to investigate the speed of naming in general.

The ethic committee Northwestern and Central Switzerland approved the study to be observational as no effect of intervention(s) on biomedical or other health related outcomes were evaluated, but only the influence of type of the visual stimulus and the response variety on correctness and naming latencies in the two participant groups.

详细描述

Qulity assurance:

To verify the presence and reliability of all subject data, the following items were checked during these visits using a checklist: Presence of informed consent, presence of all data requested in the questionnaire, correctness of the data copied from the source files (e.g. test protocols) and traceability of the data flow. At the end of the experiment, the correct storage of the data (informed consent of the study participants, identification list, raw data) were checked. All involved staff who had access to the clinical data were informed and trained about anonymization, ethical aspects and correct data manipulation and storage. Direct access to the source data and all relevant documents and records is guaranteed to the ethics committee upon request and presentation.

Data dictionary:

  • Questionnaire on personal and health-related information of the experiment participants: Frequencies, descriptive statistics
  • The Pyramids and Palm Trees test (PPTT) (Howard & Patterson 1992): passed/not passed: scores above 90% indicate correct cognitive semantics, scores below indicate impaired; 90% of the images must be correctly matched, i.e., at least 47 of 52 items.
  • Colouring of Pictures test (CoPT) (De Renzi et al. 1972): passed/not passed: In order to exclude the presence of an acquired color diagnosis due to the brain injury suffered by participants with aphasia, the ability to assign colors to objects is tested with a coloration test.
  • Picture Naming Test: Number of correct responses and naming latencies when picture stimuli are presented in two language varieties (Swiss dialect and Swiss standard language)

Data recording and source data:

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Cross Sectional

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Inclusion Criteria PWA
  • Diagnosed with minimal, light or moderate aphasia provoked by a left hemisphere cardiovascular accident
  • post-acute or chronic phase with a minimum of six weeks post onset
  • Swiss German as first language
  • sufficient language comprehension to follow the instructions during the experiment
  • attention span of minimum 45 minutes
  • no indication for dementia and if any only mild dysarthria and apraxia of speech according to the treating speech therapist
  • intact color vision
  • normal or corrected to normal vision and hearing
  • Inclusion Criteria CG
  • Swiss German as first language
  • No neurological diseases in their health history
  • Intact color vision
  • Normal or corrected to normal vision and hearing

排除标准

  • Exclusion Criteria PWA
  • Not fulfilling the above inclusion criteria
  • Severe aphasia
  • Aphasia with an associated disorder in the area of access to semantic object information, as indicated by performance on The Pyramids and Palm Trees Test (PPTT)
  • Exclusion Criteria CG
  • Not fulfilling the above inclusion criteria

结局指标

主要结局

Naming correctness

时间窗: Data were assessed during picture naming test on the test day (upto 1 month after inclusion).

The degree of correctness or incorrectness of the responses was coded manually following defined criteria. Response of the naming task was considered correct if the participant provided exclusively the previously defined reaction to the stimuli within 10 seconds. To be defined as extended correct response the reaction had to be classified as a synonym or a diminutive of the requested term. Responses describing a generic concept (e.g. "dog" instead of "poodle"), providing too much specification (e.g. rain coat instead of coat) were accounted as extended correct. The same applied for plural forms given instead of singulars.

Naming latencies

时间窗: Data were assessed during picture naming test on the test day (upto 1 month after inclusion).

Naming latencies were only calculated for correct responses. Each naming latency was calculated as an interval by measuring the onset of correct target response following after the onset of visual naming stimulus on the tablet screen. Naming latencies were manually measured through using the speech analysis program Praat (Boersma, 2001), which allows acoustic analysis by presenting waveform and spectrogram of audio data. Limit: 999 characters.

次要结局

未报告次要终点

研究者

发起方
Simone Hemm-Ode
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Simone Hemm-Ode

Professor

University of Applied Sciences and Arts Northwestern Switzerland

研究点 (19)

Loading locations...

相似试验

Picture Naming in the Context of Image Type and... | 临床试验