A Randomised controlled tiral to evaluate the efficacy of low molecular-weight heparin on pregnancy outcome of women with previus pregnancy complication - Heparin for prevention of pregnancy complication

OSPEDALE MAGGIORE DI MILANO IRCCS0 个研究点目标入组 266 人开始时间: 2007年1月10日最近更新: 2022年4月4日

适应症

试验速览

暂无简介。

•1 History of at least 1 a pre-eclampsia blood pressure 140/90 mmHg on two or more occasions occorring 20 weeks of gestation, together with proteinuria 0,3g/24h or 3 dipstick testing or oclampsia defined as the presence of new onest seizures in a preclamptic patients 22 b HELLP Hemolysis, helevated liver enzymes and low platelet syndrome the following laboratory findings in combination 1 hemolysis lactic dehidrogenase 600IU/l or serum bilirubin 1.2mg/dl or presence of schistocytes in the peripheral blood ; 2 increased serum AST concentration 70UL/l ; 3 Thrombocytopenia PLT below 100,000/mm3 c placental abruption d fetal growth restriction defined as 1 birthwight below the 10th percentile for gestational ege. And 2 a percentile reduction of the abdominal circumference 40 by ultrasaund US 23,24 ; e spontaneus pregnancy loss 15th gestational week. f At last 2 early spontaneus pregnancy losses below 15th gestational week ; 2 previus obstetrical complication not associatede with an antomical, chromosomical, endocrine, traumatic or infectius cause; 3 Present at less than 12 weeks gestation with a postitive pregnency test and confirmatory US 4 give written Informed Consent
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range
•F.1.3 Elderly (>=65 years) no
•F.1.3.1 Number of subjects for this age range

•1 previus obstetrical complication associated with an antomical, chromosomical, endocrine, traumatic or infectius cause; 2 History of venous

发起方

OSPEDALE MAGGIORE DI MILANO IRCCS