EUCTR2010-018249-78-GB进行中（未招募）不适用
Small Particle Inhaled Steroids in Refractory Steroid-responsive Asthma - Small Particle Steroids in Asthma. V1
niversity of Nottingham0 个研究点开始时间: 2010年3月18日最近更新:
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •Non-smokers with refractory asthma (ACQ score =1.5 or requirement for oral steroids =twice per year despite treatment with high dose inhaled steroid and treatment with, or unsuccessful trial of, a long acting beta-2 agonist or leukotriene antagonist).
- •Sputum eosinophil count >3%
- •A response to a 2 week trial of oral steroids, defined as a reduction in ACQ score by 0.5, an increase in FEV1 of 200ml, or either normalisation or a fall in exhaled NO of =25 ppb.
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range
排除标准
- •Poor compliance with usual asthma treatment
- •Pregnancy, inadequate contraception or lactation
- •Active smoking or smoking history of >10 pack-years
- •Clinical diagnosis of ABPA or significant bronchiectasis
- •Another significant, active, medical co-morbidity
- •Use of a medication which interacts with ciclesonide (ketoconazole, itraconazole, ritonavir, nelfinavir)
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