Pattern and Surgical Outcome of Papillary Thyroid Cancer: A Case Series Study at Sohag University Hospitals
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 30
- 主要终点
- Prevalence of Extrathyroidal Extension in Papillary Thyroid Carcinoma
研究概览
简要总结
The aim of this study is to evaluate the clinicopathological pattern and surgical outcome of papillary thyroid carcinoma (PTC) at Sohag University Hospitals. This will help improve local risk stratification, optimize surgical decision-making, and guide future management strategies for patients with PTC in this region.
详细描述
Papillary thyroid carcinoma (PTC) is the most common histological subtype of thyroid cancer, representing about 80-85% of cases. This study is a case-series study with both retrospective (June 2023 - June 2026) and prospective (June 2026 - March 2027) components, conducted at the Department of General Surgery, Sohag University Hospitals.
All patients diagnosed with papillary thyroid carcinoma and managed at Sohag University Hospitals during the study period will be included. Data collection includes baseline demographic and clinical features, preoperative laboratory tests (thyroid function tests and serum calcium), neck ultrasonography findings (ACR TI-RADS category, nodule size, and lymph node assessment), fine-needle aspiration cytology (Bethesda System), surgical intervention types (hemithyroidectomy, total thyroidectomy, and neck dissection), final histopathological characteristics (tumor size, multifocality, lymphovascular invasion, extrathyroidal extension, and nodal status), and early postoperative complications (hypocalcemia, recurrent laryngeal nerve palsy, hematoma, seroma, and wound sepsis).
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Other
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All patients diagnosed with papillary thyroid carcinoma and its variants managed at Sohag University Hospitals.
- •Confirmation of diagnosis histopathologically.
- •Availability of sufficient clinical, radiological, operative, and pathological data for analysis.
排除标准
- •Patients diagnosed with other types of thyroid malignancy (e.g., follicular, medullary, or anaplastic carcinoma).
- •Patients with a history of previous thyroid surgery before presentation to the study setting.
- •Patients with incomplete essential medical records that prevent confirmation of diagnosis or extraction of main study variables.
研究组 & 干预措施
patients with papillary thyroid carcinoma
All patients diagnosed with papillary thyroid carcinoma (and its variants) managed at Sohag University Hospitals during the study period (June 2023 to March 2027).
结局指标
主要结局
Prevalence of Extrathyroidal Extension in Papillary Thyroid Carcinoma
时间窗: 9 months
Percentage of participants with histologically confirmed extrathyroidal extension.
次要结局
- Rate of Cervical Lymph Node Metastasis(9 months)
- Incidence of Early Postoperative Surgical Complications(9 months)
- Incidence of Multifocal Papillary Thyroid Carcinoma(9 months)
研究者
Ahmed Abolabd Ahmed
Resident Physician, Department of General Surgery, Sohag University Hospitals
Sohag University