Different Risk Stratification Models for Prediction of Lymph Node Involvement in Endometrial Carcinoma
Completed
- Conditions
- Endometrial Cancer
- Interventions
- Procedure: hysterectomy
- Registration Number
- NCT04120649
- Lead Sponsor
- Assiut University
- Brief Summary
Endometrial cancer is the most common malignant disease of the female genital tract and the seventh most common cause of cancer death in women in Western countries. Histological type, grade and depth of myometrial invasion are prognostic factors in early stage disease as well as risk factors for lymph node metastasis. Systematic lymphadenectomy has recently been questioned for stage I disease based on the results from two randomized trials
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 50
Inclusion Criteria
- Not virgin
- Not having congenital anomalies
- Early stage
- Body mass index less than 35
Exclusion Criteria
- virgin
- advanced stage
- sever infection especially in the pelvis
- lymphadenopathy for any cause
- lymphadenectomy for any cause
- BMI more than 35
- Synchronous malignancies
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description endomterial cancer hysterectomy All patients visiting the clinic at Women Health Hospital who having endometrial carcinoma with their diagnosis based on investigations (tumor marker ) , imaging, histopathology will have surgical staging consisted of total hysterectomy, bilateral salpingo-oopherectomy (based on the age of the patient), pelvic and para-aortic lymphadenectomy, and peritoneal washings
- Primary Outcome Measures
Name Time Method the validity of Mayo criteria risk stratification model 3 months risk stratification model for prediction of lymph node involvement in women with endometrial carcinoma
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Ahmed Abbas
🇪🇬Assiut, Cairo, Egypt