Mitomycin, ifosfamide and cisplatin in non-small cell lung cancer (NSCLC): A randomised trial of chemotherapy plus radiotherapy versus radiotherapy alone
- Conditions
- ung (non-small cell) cancerCancerLung (non-small cell)
- Registration Number
- ISRCTN56319613
- Lead Sponsor
- Cancer Research UK (CRUK) (UK)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 0
1. Age 75 years or under
2. Histologically or cytologically proven non-small cell lung cancer, ie adeno- squamous or large cell carcinoma
3. Clinically or radiologically evaluable disease 4. Inoperable, but clinically limited stage disease
5. WHO performance status of 0-2
6. No previous chemotherapy or radiotherapy
7. No metastatic disease, except ipsilateral stem cell factor (SCF) lymphadenopathy
8. Normal renal function
9. No other previous or concurrent malignancy, except cone biopsied carcinoma in-situ of the cervix and adequately treated basal cell carcinoma of the skin
10. No pleural effusion or symptomatic superior vena cava obstruction
11. No pre-existing severe impairment of lung function likely to prejudice the safe administration of the proposed radiotherapy
12. No indication that protocol treatment would exacerbate a serious pre-existing medical condition
Not provided at time of registration
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ot provided at time of registration
- Secondary Outcome Measures
Name Time Method ot provided at time of registration