NCT03342820CompletedNot Applicable
Impact of Muscular Fatigability on Spastic Co-contractions Between the Quadriceps and Hamstrings in Stroke Patients
University Hospital, Lille1 site in 1 country30 target enrollmentStarted: January 19, 2018Last updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 30
- Locations
- 1
- Primary Endpoint
- Cocontraction Index (CCI) between the rectus femoris and the semitendinosus
Study Overview
Brief Summary
This study evaluates the effects of an isokinetic fatigue protocol of the quadriceps on the amount of co-contractions of this last with the hamstrings during a maximal isometric flexion movement in hemiparetic stroke patients.
The effect of such a protocol on gait parameters and spasticity of the quadriceps will be evaluated also.
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Intervention Model
- Single Group
- Primary Purpose
- Basic Science
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to 80 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Age between 18 and 80y
- •Hemiparesis after a first-ever stroke > 3 months
- •Spasticity of the quadriceps muscle
- •Quadriceps strength at least at 3/5 (MRC testing)
- •Subject able to walk at least 2min without rest
- •Informed consent
- •Social security affiliation
Exclusion Criteria
- •Severe comprehension troubles (language, cognitive or psychiatric disorders)
- •History of previous stroke, locomotor or other neurological disorders
- •Locomotor troubles affecting the paretic arm
- •Contraindication to efforts : cardiac insufficiency, severe aortic valvular stenosis, recent heart failure, non treated high blood pressure, severe peripheral arterial disease
- •Pregnancy or breastfeeding
- •Adult subject to guardianship
Outcomes
Primary Outcomes
Cocontraction Index (CCI) between the rectus femoris and the semitendinosus
Time Frame: one day
ratio of the RMS of a the rectus femoris when acting as antagonist to the effort intended (knee flexion) to the RMS of the same muscle when acting as an agonist during a reciprocal maximal isometric knee flexion effort (500 ms around the peak of rectified EMG
Secondary Outcomes
- 10 metre walk test (10MWT)(one day)
- Isometric peak knee flexion torque(one day)
- Cocontraction Index (CCI) between the other parts of the quadriceps and the semitendinosus muscle(one day)
- Spasticity of the quadriceps(one day)
- 2 minute walk test (2MWT)(one day)
- Agonist Recruitment Index of the semitendinosus(one day)
- Isometric peak knee extension torque(one day)
- perceived exertion at the end of the 2MWT (Borg Scale 6-20)(one day)
- spatio-temporal gait parameters at comfortable speed(one day)
Investigators
Study Sites (1)
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