Effect of oral MgSo4 administration on plasma, inflammation marker, anti oxidant capacity, lysyl peroxidase, ox-LDL, LOX-1 levels and lipid profiles in atherosclerosis patients
- Conditions
- Patients with high blood pressure and Hyperlipidemic with a small plaque in one of the coronary arteries.Atherosclerotic heart disease of native coronary artery without angina pectorisI25.10
- Registration Number
- IRCT20151028024756N3
- Lead Sponsor
- Bandare-abbas University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 100
1. Moderate coronary artery disease<60 -2. Age of women and men should be more than 55 years and 45 years respectively. 3.Also people that are diabetic, hypertension, hyperlipidemia , smoker and insulin resistance will be entered in the study.
1.Age of women be less than 55 years,2. pregnant women3. patients who are using magnesium and calcium containing supplements 4. patients who have experienced renal insufficiency (serum creatinine levels more than 1.3 mg/dl in women and more than 1.5 mg/dl in men). 5- elevated hepatic enzymes (more than 3 folds over normal values),recent infections (less than one month prior to study) and chronic inflammatory diseases, cerebrovascular accident(CVA), also cancer and drug sensetivity
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Hypertension- Hyperlipidemic- Atherosclerosis. Timepoint: every three months. Method of measurement: Barometer device and appropriate kits.
- Secondary Outcome Measures
Name Time Method Size of Atherosclerosis plaque. Timepoint: After one year. Method of measurement: With Angiography if patient satisfies.