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Immunogenicity and safety of the BBIBP-CorV COVID-19 vaccine in adolescent in Thailand

Phase 2
Recruiting
Conditions
The immune response the BBIBP-CorV COVID-19 vaccine in adolescent in Thai population.
COVID-19 vaccine, Sinopharm, adolescent, safety, immunogenicity
Registration Number
TCTR20210920005
Lead Sponsor
Chulabhorn Royal Academy
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
500
Inclusion Criteria

1. age 12-30 year old
2. no active underlying disease.
3. informed to participated the study.

Exclusion Criteria

1. previous infection with SAR-CoV-2
2. previous received SAR-CoV-2 vaccine
3. receive any vaccine with 14 days
4. Fever at vaccination day
5. History of URI within 14 days
6. History of seizure.
7. Abnormal development
8. Pregnancy.
9. Lactation.
10. History of severe allergy to vaccine.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Geomatric mean ratio (GMR) of anti-RBD of SARS-CoV-2 between adolescent group and adult group 4 week after second shot Anti-RBD antibodies level
Secondary Outcome Measures
NameTimeMethod
Safety profile within 30 days after vaccination at day1, day7, and day30 Adverse events questionare
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