The SANT-study - A randomized controlled clinical trial of Streptococcus group A-negative acute tonsillitis in primary health care - a comparison of phenoxymethylpenicillin and no antibiotic treatment
Phase 1
Recruiting
- Conditions
- TonsilitisTherapeutic area: Diseases [C] - Respiratory Tract Diseases [C08]
- Registration Number
- CTIS2023-508542-18-00
- Lead Sponsor
- Region Joenkoepings Laen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 390
Inclusion Criteria
Adult and young adult persons ages 15 years and older with symptoms of sore throat and or pain on swallowing, Centor score 3-4: absence of cough, anamnestic fever (temperature above 38.5°C), tender lymphadenitis, and tonsillar exudates (one or both tonsils), Duration of symptoms < 8 days, A RADT for GAS taken, Willing and able to give informed consent. Subjects under 18 years of age must in addition have the consent from both parents/caretakers
Exclusion Criteria
Ongoing antibiotic treatment, Known or suspected allergies to penicillin, Strong suspicion of mononucleosis and positive point of care test, Suspicion of PTA or indication for admittance
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method