A Randomized Controlled Trial to Evaluate the Efficacy of Gomutra Bhavita Lohbhasma with Milk in the Management of Pandu with Special Reference to Iron Deficiency Anemia

Anemia, particularly iron deficiency anemia, is a major global health concern, affecting a large proportion of the population, especially women and children in developing countries like India. The present study is a randomized controlled trial designed to evaluate the efficacy of Gomutra Bhavita Lohabhasma with milk in the management of Pandu with special reference to iron deficiency anemia. Lohabhasma, an Ayurvedic formulation, is traditionally used to replenish iron stores and enhance hematopoiesis. The Bhavana process with Gomutra is believed to potentiate its efficacy and detoxify the metal component, while milk as an adjuvant supports nourishment and reduces gastrointestinal irritation. The study will include 141 participants randomly divided into three groups: Group I will receive Gomutra Bhavita Lohabhasma with milk, Group II will receive the same drug with water, and Group III will receive standard iron supplementation. The treatment period will be 8 weeks with follow up every 15 days. Hemoglobin and other hematological parameters, along with clinical symptoms of anemia, will be assessed before and after treatment. This research aims to validate the traditional Ayurvedic approach using modern clinical methodology and to explore a safe, effective, and culturally acceptable alternative in the management of iron deficiency anemia.