Use of Air Purifiers to Improve Respiratory Health in Children
- Conditions
- Asthma in Children
- Interventions
- Device: Rensair Compact air purifier unit
- Registration Number
- NCT05817357
- Lead Sponsor
- University of Liverpool
- Brief Summary
The goal of this pilot study is to investigate if installing an air purifier in the homes of children and young people with asthma improves their asthma outcomes.
The main questions it aims to answer are:
* Does installing an air purifier in the homes of children and young people with asthma improve their asthma outcomes
* Is the use of an air purifier in the home acceptable to children and young people and their families?
Children and young people with asthma attending our clinic will be selected at random to be invited to take part. For those that take part, an air purifier (Rensair Ltd. - Rensair Compact) will be installed in their home for a one-year period. Data will be collected on numbers of asthma attacks, rescue oral steroids, quality of life, symptoms, lung function at the beginning and at three-monthly intervals throughout the study period. The acceptability to children and young people and their families taking part in this study of using an air purifier in their home will also be assessed.
- Detailed Description
The goal of this pilot study is to investigate if installing an air purifier in the homes of children and young people with asthma improves their asthma outcomes.
The main questions it aims to answer are:
* Does installing an air purifier in the homes of children and young people with asthma improve their asthma outcomes (including reduction in asthma exacerbations, improvement in symptom control, improvement in quality of life).
* Is the use of an air purifier in the home acceptable to children and young people and their families?
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 20
- Aged 5 to 15 years old
- Attend the asthma clinic in our hospital
- Have a confirmed physician-diagnosis of asthma from the asthma clinic
- Live in mainland England (this is due to delivery of the air purification units and also associated maintenance of them)
- Nil specific other than not meeting inclusion criteria
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Installation of air purifier (Rensair Ltd - Rensair Compact) Rensair Compact air purifier unit Rensair Compact air purifier unit will be installed in the homes of all children/young people participating in this study for a period of one-year.
- Primary Outcome Measures
Name Time Method Asthma control test score 12 months Asthma control test (ACT) or child asthma control test score (cACT) - depending on age of participant - the higher the score the better the asthma control
Number of parent/carer work days missed due to their child's asthma 12 months Number of work days missed due to child's asthma - assessed by questionnaire
Quality of life - mini paediatric asthma quality of life questionnaire score 12 months Quality of life using mini paediatric asthma quality of life questionnaire - the higher the score the better the quality of life
Amount of asthma reliever medication use per week 12 months Amount of use of asthma reliever medication use over a one week period (assessed as a categorical value)
Measurement of fraction of exhaled nitric oxide (FeNO) 12 months Fraction of exhaled nitric oxide measurements
Forced expired volume in one second (FEV1) 12 months Spirometry measurements using ERS/ATS criteria and Global Lung Initiative Reference z-score
FEV1:FVC 12 months Spirometry measurements using ERS/ATS criteria and Global Lung Initiative Reference z-score
Number of asthma exacerbations (asthma attacks) 12 months Asthma attacks and unscheduled healthcare visits due to acute asthma (including ED attendance, admission, GP/primary care attendance) - assessed by questionnaire and hospital-recorded attendances/admissions
Number of rescue oral steroid courses 12 months Number of rescue oral steroid courses - assessed by questionnaire and prescription data
Number of school days absent due to asthma 12 months Number of school days missed due to asthma - assessed by questionnaire
Forced vital capacity (FVC) 12 months Spirometry measurements using ERS/ATS criteria and Global Lung Initiative Reference z-score
Acceptability to children and families participating of using an air purifier in their home 12 months Acceptability to children and young people and their families taking part in the study in terms of use of air purifier in their homes - assessed by questionnaire
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Alder Hey Children's Hospital
🇬🇧Liverpool, Merseyside, United Kingdom