Safe and sustainable balanced anesthesia – identifying potentials in daily clinical routine
Recruiting
- Conditions
- balanced anesthesiainhalation anesthesia
- Registration Number
- DRKS00029400
- Lead Sponsor
- Klinik für Anästhesiologie, Uniklinikum RWTH Aachen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 251
Inclusion Criteria
•=18 years
•ASAI-II
•MET=4
•General anesthesia with sevoflurane
•Elective surgery with intubation
Exclusion Criteria
•Not willing to participate
•not able to provide informed consent
•pregnancy
•BMI=30kg/m2 and <18kg/m2
•severe respiratory disease
•single lung ventilation
•cardiac and thoracic surgery
•extracorporeal membrane oxygenation
•emergency surgery
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Sevoflurane consumption in ml during induction of anesthesia (cumulative amount in the first 7 minutes after opening of vaporizer 1)
- Secondary Outcome Measures
Name Time Method - Sevoflurane consumption in ml during maintenance<br>- Ventilation settings: Fresh gas flow, Vaporizer setting, Fraction of inspiratory and expiratory oxygen, endtidal sevoflurane concentration<br>- minimal alveolar concentration (MAC)<br>- Ventilation complications: laryngospasm, bronchospasm <br>- Narcotic depth: neuromonitoring, need for additional propofol bolus <br>- Hemodynamic stability: mean arterial blood pressure, need for vasopressors, bradycardia/tachycardia<br>- Economic efficiency: Cost savings <br>- Sustainability: CO2 equivalents