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Efficacy of Folrex in the Superior Extremity Rehabilitation After Acute Stroke

Phase 3
Completed
Conditions
Stroke
Interventions
Drug: Folrex
Drug: Placebo
Registration Number
NCT01016119
Lead Sponsor
Catalysis SL
Brief Summary

The purpose of the study is to evaluate whether Folrex, could improve the motor recovery of the upper extremity after stroke in comparison with placebo during 4 weeks of treatment.

Detailed Description

Periodical measures of the motor recovery, of the upper extremity, by Fugl-Meyer score, it will be done at the beginning, at fifth day and at month. Each value will be compare to evaluate whether the groups of patient improve.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
40
Inclusion Criteria
  • Patients with acute stroke < 24 hours.
  • Patients with impairment up to 4 on NIHSS scale.
  • Family support.
  • Informed consent.
Exclusion Criteria
  • Presence of another disease not well controlled.
  • Patient with dementia.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
FolrexFolrexIn this group we will use Folrex cream, in the early rehabilitations in the upper extremity
PlaceboPlaceboIn this group we will use Placebo cream, in the early rehabilitations in the upper extremity
Primary Outcome Measures
NameTimeMethod
Periodical measures of the motor recovery, of the upper extremity, by Fugl-Meyer score, it will be done at the beginning, at fifth day and at month (4 weeks).4 weeks
Secondary Outcome Measures
NameTimeMethod
Barthel index4 weeks
National Institutes of Health Stroke Scale (NIHSS)4 weeks

Trial Locations

Locations (1)

Salvador Allende Hospital

🇨🇺

Havana City, Havana, Cuba

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