Postoperative Pulmonary Complications Between Patients Undergoing Abdominal Surgery in Plateau and Plain Areas

• Conditions: Postoperative Pulmonary Complications;Abdominal Surgery

• Registration Number: NCT05131009
• Lead Sponsor: Wuhan Union Hospital, China

Brief Summary

This study aims to collect perioperative diagnosis and treatment information of patients undergoing abdominal surgery at plateau and plain areas , collect blood and others samples for laboratory testing when necessary, analyzing the data to clarify the incidence and risk factors of pulmonary complications in patients undergoing abdominal surgery at different altitudes, so as to reduce the risk of pulmonary complications and even death in clinical practice.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2021-10-25
• Status Verified: 2021-11
• Study Start: 2021-11
• Study First Submitted QC: 2021-11-10
• Last Update Submitted: 2021-11-10
• Study First Posted: 2021-11-23
• Last Update Posted: 2021-11-23
• Primary Completion: 2022-09
• Study Completion: 2022-09

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 600

Inclusion Criteria

1. ≥ 18 years old；
2. scheduled for elective abdominal surgery under general anesthesia；
3. ASAⅠ-Ⅲ

Exclusion Criteria

1. Patients and their family members refused to be enrolled；
2. patients were unable to communicate because of language disorders such as dementia and hearing impairment；
3. patients were admitted to ICU 48 hours before operation；
4. preoperative diagnosis of ARDS, aspiration pneumonia, pulmonary embolism or pulmonary edema or other acute respiratory diseases；
5. mechanical ventilation within one week before operation；
6. death or discharge within 24 hours after operation；
7. second operation due to postoperative complications

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
incidence and risk factors of pulmonary complications	1 week after surgery

Secondary Outcome Measures

Name	Time	Method
Biomarkers	1 week after surgery
incidence of Major Extrapulmonary Complications	within the 30 days after surgery
ventilation duration,length of stay in ICU and Hospital Stay and death	within the 30 days after surgery
incidence and risk factors of various specific pulmonary complications	1 week after surgery

Trial Locations

Locations (1)

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology; 🇨🇳 Wuhan, Hubei, China