Differences in Incidence and Risk Factors of Postoperative Pulmonary Complications Between Patients Undergoing Abdominal Surgery in Plateau and Plain Areas

Wuhan Union Hospital, China1 site in 1 country600 target enrollmentNovember 2021

ConditionsPostoperative Pulmonary Complications;Abdominal Surgery

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Postoperative Pulmonary Complications;Abdominal Surgery
Sponsor: Wuhan Union Hospital, China
Enrollment: 600
Locations: 1
Primary Endpoint: incidence and risk factors of pulmonary complications
Last Updated: 4 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

This study aims to collect perioperative diagnosis and treatment information of patients undergoing abdominal surgery at plateau and plain areas , collect blood and others samples for laboratory testing when necessary, analyzing the data to clarify the incidence and risk factors of pulmonary complications in patients undergoing abdominal surgery at different altitudes, so as to reduce the risk of pulmonary complications and even death in clinical practice.

Registry

clinicaltrials.gov

Start Date

November 2021

End Date

September 2022

Last Updated

4 years ago

Study Type

Observational

Sex

All

Investigators

Sponsor

Wuhan Union Hospital, China

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•≥ 18 years old；
•scheduled for elective abdominal surgery under general anesthesia；

Exclusion Criteria

•Patients and their family members refused to be enrolled；
•patients were unable to communicate because of language disorders such as dementia and hearing impairment；
•patients were admitted to ICU 48 hours before operation；
•preoperative diagnosis of ARDS, aspiration pneumonia, pulmonary embolism or pulmonary edema or other acute respiratory diseases；
•mechanical ventilation within one week before operation；
•death or discharge within 24 hours after operation；
•second operation due to postoperative complications

Outcomes

Primary Outcomes

incidence and risk factors of pulmonary complications

Time Frame: 1 week after surgery

Secondary Outcomes

Biomarkers(1 week after surgery)
incidence of Major Extrapulmonary Complications(within the 30 days after surgery)
ventilation duration,length of stay in ICU and Hospital Stay and death(within the 30 days after surgery)
incidence and risk factors of various specific pulmonary complications(1 week after surgery)