Endoscopic Full Thickness Plication for esophageal abnormal acid exposure post Peroral endoscopic myotomy
Not Applicable
- Conditions
- Health Condition 1: K220- Achalasia of cardia
- Registration Number
- CTRI/2019/06/019819
- Lead Sponsor
- Endoscopy Research Foundation
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Patients of either sex aged 18-70 years and above
2. Aachalasia cardia patients minimum 3 months post POEM with abnormal 24hr pH metry, regardless of symptoms
3. Abnormal esophageal acid exposure defined as percentage time esophageal pH less than 4 of more than 4.2% on pH-metry during 24-h period while off PPI for atleast 1 week
4. Patients agreeing to informed consent
Exclusion Criteria
1. Failed POEM â?? elevated integrated relaxation pressure and lower esophageal sphincter pressure
2. Hiatus hernia hills 3 or more
3. Patients with significant renal or liver disease
4. Grade D esophagitis
5. Barrettâ??s esophagus
6. ASA physical status >II
7. Pregnancy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Improvement of abnormal acid exposure by 24 hr ph studyTimepoint: 1 month
- Secondary Outcome Measures
Name Time Method Improvement in GERD-QTimepoint: 1 month and 3 months