Quantification of Transition Metals in Patients at the Cologne University Hospital
试验速览
- 阶段
- 不适用
- 入组人数
- 3,000
- 试验地点
- 1
- 主要终点
- Transition metal concentration
研究概览
简要总结
In this trial, concentrations of transition metals of interest are quantified in surplus cerebrospinal fluid (CSF) and blood serum samples. Quantification of the transition metals will be performed by inductively coupled plasma mass spectrometry (ICP-MS). The treating physicians as well as the patients will not be informed about the results of drug concentrations.
详细描述
Samples used include:
Remaining portions of samples collected for diagnostic or therapeutic reasons (paired CSF and blood serum samples). No lumbar puncture will be done specifically for this protocol.
The objective of this study is to gain an overview about transition metals concentrations in blood serum and CSF in order to provide preliminary data on patients. The effect of neurodegenerative diseases on metals or the other way round will be assessed if possible.
研究设计
- 研究类型
- Observational
- 观察模型
- Ecologic Or Community
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •The trial will include any patient (with various diseases, especially neurodegenerative diseases) who received a lumbar puncture.
排除标准
- •• The lower age limit is 18 years. In concordance with the objective of the project there is no specific exclusion criteria.
结局指标
主要结局
Transition metal concentration
时间窗: 5 years
次要结局
未报告次要终点
研究者
Ali Mohammad Nejad Sigaroudi
Quantification of Transition Metals in Patients at the Cologne University Hospital
University of Cologne