Utility of MRI With Doppler Ultrasound Gating for Advanced Fetal Monitoring
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Congenital Heart Disease
- Sponsor
- The Hospital for Sick Children
- Enrollment
- 3
- Locations
- 1
- Primary Endpoint
- Comparison between fetal MRI and fetal echocardiography
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
We will test an ultrasound device that uses sound waves to detect the fetal heart beat, and use this device to tell the MRI scanner when to collect pictures of the fetal heart. This will help freeze motion of the fetal heart, to make MRI pictures sharper. This will be important for assessing human fetal heart disease, an active area of research at our institution.
Investigators
Mike Seed
Qualified Investigator
The Hospital for Sick Children
Eligibility Criteria
Inclusion Criteria
- •pregnant adults (age 18 and up) with fetus affected by congenital heart disease
- •singleton pregnancy in their 2nd and 3rd trimesters
- •scheduled for a clinical fetal ultrasound examination at the Fetal Echocardiography Clinic at SickKids
Exclusion Criteria
- •claustrophobia
- •cardiac pacemaker
- •non-MRI compatible implants
- •non-singleton pregnancy
- •obesity (BMI \> 30)
Outcomes
Primary Outcomes
Comparison between fetal MRI and fetal echocardiography
Time Frame: within 2 weeks of participation in the study
Anatomic MR images of the fetal heart will be acquired using prospective gating information from the Doppler ultrasound probe (SMART-SYNC LM03) and used to calculate ejection fraction. These values will be compared with corresponding reference values obtained during the patient's visit to the Fetal Echocardiography Clinic.