Utility of MRI With Doppler Ultrasound Gating for Advanced Fetal Monitoring
- Conditions
- Congenital Heart Disease
- Interventions
- Device: SMART-SYNC LM03
- Registration Number
- NCT03541291
- Lead Sponsor
- The Hospital for Sick Children
- Brief Summary
We will test an ultrasound device that uses sound waves to detect the fetal heart beat, and use this device to tell the MRI scanner when to collect pictures of the fetal heart. This will help freeze motion of the fetal heart, to make MRI pictures sharper. This will be important for assessing human fetal heart disease, an active area of research at our institution.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 3
- pregnant adults (age 18 and up) with fetus affected by congenital heart disease
- singleton pregnancy in their 2nd and 3rd trimesters
- scheduled for a clinical fetal ultrasound examination at the Fetal Echocardiography Clinic at SickKids
- claustrophobia
- cardiac pacemaker
- non-MRI compatible implants
- non-singleton pregnancy
- obesity (BMI > 30)
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description SMART-SYNC LM03 SMART-SYNC LM03 All participants
- Primary Outcome Measures
Name Time Method Comparison between fetal MRI and fetal echocardiography within 2 weeks of participation in the study Anatomic MR images of the fetal heart will be acquired using prospective gating information from the Doppler ultrasound probe (SMART-SYNC LM03) and used to calculate ejection fraction. These values will be compared with corresponding reference values obtained during the patient's visit to the Fetal Echocardiography Clinic.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
The Hospital for Sick Children
🇨🇦Toronto, Ontario, Canada