iCBT for Adult Obsessive-Compulsive Disorder

Not Applicable

Not yet recruiting

• Conditions: Obsessive-Compulsive Disorder (OCD)

• Registration Number: NCT07081438
• Lead Sponsor: Hospital Clinic of Barcelona

Brief Summary

The goal of the study is to assess the feasibility, acceptability, and potential effects of therapist-guided internet-delivered cognitive-behavior therapy (iCBT) for adult obsessive-compulsive disorder, using a recently developed digital platform.

Detailed Description

Although cognitive-behavior therapy (CBT) is a well-established first-line treatment for many mental disorders, very few patients receive it due to the shortage of trained professionals, the costs of face-to-face therapy, and geographic barriers. Therapist-guided internet-delivered CBT (iCBT) is a potential solution to this problem but is not generally available in our context.

The investigators plan to:

1. Develop a digital platform for the treatment of mental disorders using therapist-guided iCBT;

2. Assess the feasibility, acceptability, and potential effects of therapist-guided iCBT for adult obsessive-compulsive disorder (OCD) using the platform developed in Objective 1.

Study Timeline

• Status Verified: 2025-07
• Study First Submitted: 2025-07-10
• Study First Submitted QC: 2025-07-22
• Study First Posted: 2025-07-23
• Last Update Submitted: 2025-07-29
• Last Update Posted: 2025-07-31
• Study Start: 2025-09-01
• Primary Completion: 2027-01-01
• Study Completion: 2027-03-01

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 25

Inclusion Criteria

• Age between 18 and 75
• Internet access
• Principal diagnosis of OCD, based on DSM-5
• Yale-Brown Obsessive-Compulsive Scale (Y-BOCS) Total Severity Score > 16
• Ability to communicate in Spanish
• For participants taking psychotropic medication for OCD: at least eight weeks on stable medication and willingness to stay on the same medication/doses for the 12 weeks of the study

Exclusion Criteria

• Estimated IQ < 70, as per the Vocabulary subtest of the Wechsler Adults Intelligence Scale for Children (WISC)
• Eight or more previous sessions of CBT for OCD with an experienced therapist during the last 12 months
• Ongoing psychological treatment for OCD
• Diagnosis of organic brain disorder, intellectual disability, autism spectrum disorder, psychosis, bipolar disorder, low-weight anorexia nervosa, or alcohol/substance dependence
• Immediate risk to self or others (e.g., suicidality)
• Inability to communicate in Spanish
• Low motivation to participate (i.e., the patient does not believe the therapy will be helpful at all)
• Insufficient time to work on the treatment (about 30 minutes per day)

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Feasibility (recruitment and retention rates and therapist burden)	From enrollment to the end of treatment at 12 weeks	The investigators will assess feasibility by recording recruitment rates, retention rates, and therapist burden (time spent by the therapist sending emails, reviewing materials, etc.).