Evaluation of the effect of broccoli-supplements intake on blood antioxidant levels and search for new biomarkers
Not Applicable
- Conditions
- Healthy adults
- Registration Number
- JPRN-jRCTs021210018
- Lead Sponsor
- Itoh Ken
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
Subjects who satisfies all follwing criteria.
1.Healthy adults aged >= 20 years to =< 35 years at the start of the trial.
2.Who can make self-judgment, voluntarily agree to participate to this trial, and provide written informed consent.
3.Those who are judged to have high SFN absorption efficiency in a preliminary study of 20-40 people.
Exclusion Criteria
1. Subjects who have food allergy to the test supplements
2. Subjects who are pregnant, will hope pregnancy, or breast-feed during the study period
3. Subjects who suffer from psychiatric disease or express psychiatric symptoms
4. Subjects who join other clinical trials
5. Subjects who are judged unsuitable for this trial by the principal investigator
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Antioxidant capacity of plasma (GSH, GSSH, GSH polysulfides, GSSG, Oxidized GSH polysulfides, GSH/GSSG, Cysteine (Cys), CysSSH, Cys polysulfides, Cystine, Oxidized Cys polysulfides, Cys/Cystine, Homocysteine, Homocysteine persulfide, Bis-S-HPE-AM, Bis-SS-HPE-AM, BAP)<br>2. Blood metabolites
- Secondary Outcome Measures
Name Time Method 1.SFN absorption efficiency <br>2.Biochemical test (AST, ALT, T-Bil, gamma-GTP)<br>3.Relationship between SFN absorption efficiency and antioxidative level in plasma<br>4.Relationship between SFN absorption efficiency and metabolites in plasma