Respiratory Muscle Strength in Patients With NMD
Not Applicable
Terminated
- Conditions
- Neuromuscular Disease
- Interventions
- Device: Threshold PEP or IMT device Phillips-Respironics
- Registration Number
- NCT01555905
- Lead Sponsor
- University of Florida
- Brief Summary
The purpose of this study is to determine if inspiratory muscle strength training (IMST) will impact maximal inspiratory pressure and pulmonary function in patients with neuromuscular disease.
- Detailed Description
Subjects undergo a 12-week period of inspiratory muscle strength training. Respiratory strength is assessed before and after the training period.
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- All
- Target Recruitment
- 17
Inclusion Criteria
- Confirmed diagnosis of neuromuscular disease
- Clinical evidence of impaired pulmonary function
Exclusion Criteria
- Above or below age range
- No clinical evidence of impaired pulmonary function
- No diagnosis of a neuromusuclar disease
- Presence of an acute illness at time of study
- Participating in other research studies involving investigational drugs
- Diagnosis of a primary pulmonary disease
- Use of tobacco products
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Exercise Threshold PEP or IMT device Phillips-Respironics Threshold PEP or IMT device Phillips-Respironics
- Primary Outcome Measures
Name Time Method Maximal Inspiratory Pressure Baseline (pre-IMST) and 3 months (post-IMST) The primary endpoints for inspiratory muscle training efficacy will be maximal inspiratory pressure tests, a measure of respiratory strength.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
University of Florida
🇺🇸Gainesville, Florida, United States