Prediction of Secondary Neurological Deterioration in Patients With Moderate Traumatic Brain Injury

Completed

• Conditions: Traumatic Brain Injury

• Registration Number: NCT04854954
• Lead Sponsor: University Hospital, Brest

Brief Summary

Patients with moderate traumatic brain injury (mTBI) are 1,5 times more frequent than those with severe TBI and some of them will develop secondary neurologic deterioration (SND) within the first 7 days. However, identifying at risk patients of SND is still challenging. This study aimed to determine risk factors associated with SND after mTBI.

Detailed Description

Not available

Study Timeline

• Status Verified: 2021-01
• Study Start: 2021-02-03
• Primary Completion: 2021-02-22
• Study Completion: 2021-03-22
• Study First Submitted: 2021-04-19
• Study First Submitted QC: 2021-04-19
• Last Update Submitted: 2021-04-19
• Study First Posted: 2021-04-22
• Last Update Posted: 2021-04-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 142

Inclusion Criteria

• Adults
• Admitted in Brest hospital between 2015 and 2018 for moderate TBI, defined by Glasgow coma scale (GCS) score 9-13

Exclusion Criteria

• Non consenting patients

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Secondary neurologic deterioration	Within 7 days after hospital admission	SND was defined either by a decrease in GCS or by a deterioration in neurologic status sufficient to warrant intervention like mechanical ventilation, transfer to the ICU or neurosurgical intervention

Trial Locations

Locations (1)

CHRU de Brest; 🇫🇷 Brest, France