Health benefits of pulses (legumes) in older overweight adults

Not Applicable

Completed

• Conditions: Cognitive function; Cardiometabolic health; obesity; Diet and Nutrition - Obesity; Cardiovascular - Other cardiovascular diseases; Mental Health - Studies of normal psychology, cognitive function and behaviour

• Registration Number: ACTRN12611000642987
• Lead Sponsor: Associate Professor Jon Buckley

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2011-06-23
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 160

Inclusion Criteria

overweight/obese (BMI > 25kg/m2), older adults (age 50-80 years) who consume one or less serves per week of pulses.

Exclusion Criteria

1. Body weight exceeding 135kg (maximum capacity of the DEXA scanner) 2.Established cardiovascular, liver or kidney disease 3.Uncontrolled diabetes 4. Use of medication or supplements for management of elevated lipids, blood pressure or glucose that has not been stable for at least 3 months, other medication will be considered at the discretion of the investigators 5.Use of appetite suppressants or Orlistat (Xenical) 6.Inability to consume pulse-enriched foods 7.Pregnancy 8.Smoking or only recently quit smoking (within the last 12 months) 9.Weight loss of 3kg or more in the 6 months prior to enrolling in the study 10.Adherence to a weight loss diet or physical activity program designed to facilitate weight loss 11.Acute or terminal illness 12. Alcohol consumption of more than 4 standard drinks per day.13. Prostheses or implants that are considered by the investigators to influence the accuracy of the body composition scan

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Cerebral vasodilator responsiveness will be measured by Transcranial Doppler (TCD)[Baseline (week 0), week 6 and week 12]

Secondary Outcome Measures

Name	Time	Method
Body composition will be assessed by dual energy x-ray absorptiometry (DEXA, specifically fat and lean mass), weight, waist and hip circumference[Baseline (week 0), week 6 and week 12];Arterial compliance and blood pressure will be assessed by the cardiovascular profiler and automatic sphygmomanometer, respectively.[Baseline (week 0), week 6 and week 12];Lipids and lipoproteins will be assessed by serum analysis[Baseline (week 0), week 6 and week 12];Insulin sensitivity will be assessed by serum analysis[Baseline (week 0), week 6 and week 12];Cognitive function will be assessed by a battery of tests including the Rey Auditory Verbal Learning Test (RAVLT), Wechsler Adult Intelligence Scale (WAIS) IV, Controlled Oral Word Association (COWA) and Stroop[Baseline (week 0), week 6 and week 12]