NCT05575050已完成不适用
Impact of Teeth Brushing on Bacterial Microbiota and Healthcare-associated Infections in Ventilated COVID-19 Patients
University Hospital in Krakow1 个研究点 分布在 1 个国家目标入组 56 人开始时间: 2021年9月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 56
- 试验地点
- 1
- 主要终点
- Healthcare-associated infection
研究概览
简要总结
The aims of this study were:
- Observation of dynamics in oral microbiota and its association with the incidence of HAIs and VAP in mechanically ventilated COVID-19 patients in an ICU setting
- Evaluation of the incidence of HAIs and VAP and their association with oral bacteriobiota in mechanically ventilated COVID-19 patients in an ICU setting
- Assessment of impact of different oral hygienic procedures on oral microbiota, the incidence of HAI and patients' safety in mechanically ventilated COVID-19 patients in an ICU setting approaches to oral care in an ICU setting
Intervention of oral hygienic procedures implemented in study:
Patients were divided into 2 groups depending on the oral care procedure:
- Standard oral procedure (cleaning and moisturizing of oral cavity, suction of excess fluid)
- Extended oral procedure (cleaning and moisturizing of oral cavity, teeth brushing, suction of excess fluid)
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •SARS-CoV-2 infection confirmed by real-time reverse transcriptase-polymerase chain reaction (RT-PCR) assay of nasal and pharyngeal swabs upon hospital admission
- •Signed consent to participate in the study
- •Patients admitted to ICU
- •Intubation due to COVID-19 related pneumonia and acute respiratory distress syndrome (ARDS) within 24 hours preceding study procedures
排除标准
- •No consent to participate in the study
结局指标
主要结局
Healthcare-associated infection
时间窗: one month
Healthcare-associated infection (HAI) incidence was measured.
次要结局
- Oral cavity assessment(one month)
- Frequency of identification of Enterococcus fecalis, Acinetobacter baumannii, Klebsiella pneumoniae.(one month)
研究者
Mateusz Fiema
MD
University Hospital in Krakow
研究点 (1)
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