Strenght Training in Osteoporosis Prevention

Not Applicable

Active, not recruiting

• Conditions: Osteopenia or Osteoporosis

• Registration Number: NCT06733064
• Lead Sponsor: Mateusz Karnia

Brief Summary

The study involves 120 women over the age of 50.

All participants in the study take part in high-intensity strength training for 10 months.

In addition, half of the participants receive vitamin D3 at a dose of 4,000 IU/day.

The investigators hypothesize that training combined with vitamin D3 supplementation will be more effective in preventing osteoporosis than training alone.

Detailed Description

Not available

Study Timeline

• Study Start: 2024-09-02
• Primary Completion: 2024-10-30
• Status Verified: 2024-11
• Study First Submitted: 2024-11-08
• Study First Submitted QC: 2024-12-09
• Last Update Submitted: 2024-12-09
• Study First Posted: 2024-12-13
• Last Update Posted: 2024-12-13
• Study Completion: 2026-01-30

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: Female
• Target Recruitment: 120

Inclusion Criteria

• age over 50
• female

Exclusion Criteria

• ongoing cancer,
• unstabilized cardiovascular disease,
• cognitive disorders,
• radiological treatment in the last 12 months,
• other contraindications to undertaking high-intensity strength training,
• diseases affecting the skeleton such as: Paget's disease, type I diabetes mellitus,
• taking medications affecting skeletal conditions including: long-term therapy with corticosteroids, thiazides, antiretroviral drugs,
• contraindications to taking vitamin D including: hypercalcemia, nephrolithiasis, sarcoidosis, lack of cholecalciferol hydroxylase activity in the liver and kidneys.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Bone Mineral Density	Measured at 3 time points: before the experiment, after 10 months of training, and at 6 months after the end of training and supplementation.	Test to determine bone mineral density by densitometry.

Secondary Outcome Measures

Name	Time	Method
Vitamin D metabolites level	Measured at 4 time points: before the experiment, after 5 and 10 months of training, and at 6 months after the end of training and supplementation.	Measurement evaluating the levels of selected vitamin D3 metabolites by LC-MS.

Trial Locations

Locations (1)

University of Gdańsk, Faculty of Biology; 🇵🇱 Gdańsk, Poland