MedPath

The effect of Aloe vera” on the control of essential hypertensio

Phase 1
Conditions
hypertension.
Essential (primary) hypertension
Registration Number
IRCT2016040827276N1
Lead Sponsor
Zanjan University of Medical Science
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
40
Inclusion Criteria

Inclusion criteria

All women and men; presenting with uncontrolled hypertension who present to the cardiology clinics affiliated to the Zanjan University of Medical Sciences; aged 30-70; with systolic blood pressure greater than or equal to 140 and diastolic blood pressure greater than or equal to 90 mg; using 50 mg losartan for at least 6 weeks.

Exclusion Criteria

hypertension, greater than or equal to 180/110 mgHg which needs multi-drug treatment or emergency injection to control the blood pressure; Diagnosis of secondary blood pressure, e.g. Hyperaldosteronism, pheochromocytoma, Cushing syndrome, renal artery stenosis; Symptoms of End organ damage such as renal failure, congestion heart failure, myocardial infraction, cerebrovascular incidences within six months before the research starts; Sudden increase in blood pressure greater than 15mmHg in any time during the research (necessary to mention, if with increase lesser than 15 mmHg the blood pressure of the case is greater than or equal to 180/110 mmHg, he will be discarded from the study and, then, will be referred to a cardio-vascular specialist); Various Heart arrhythmias (such as blocks grades 2 and 3); Symptomatic heart valve diseases (except Mitral Valve prolapse); Renal or hepatic failure (Liver cirrhosis, Chronic active Hepatitis or autoimmune Hepatitis); Pregnancy and breastfeeding; Serum Potassium greater than 5 or less than 3.5 meq/L in the first visit; Any sort of disorder/failure (either medical or surgical), from researcher’s point of view, which can intervene the research; Taking drugs that influence blood pressure such as NSAIDs, CORTICOSTEROIDs, Oral contraceptives; Psychological disorders such as anxiety, depression, obsession, or taking Psychiatric drugs

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Blood pressure. Timepoint: one baselinemeasurement and 4 times follow up measurement every 2 weaks. Method of measurement: mmHg with sphygomanometer.
Secondary Outcome Measures
NameTimeMethod
© Copyright 2025. All Rights Reserved by MedPath