Développement d'un modèle prédictif du Risque de Survenue d'évènements Thromboemboliques Veineux Chez Les Patients Atteints de Cancer Broncho-pulmonaire métastatique
试验速览
- 阶段
- 不适用
- 入组人数
- 500
- 试验地点
- 3
- 主要终点
- venous thromboembolism at 12 months
研究概览
简要总结
Venous thrombo-embolism (VTE) is a frequent and serious complication of cancer. However, predictive tools for VTE in cancer patients is lacking.
In patients with metastatic broncho-pulmonarycancer, biochemical characteristics might help to identify patients at high risk for VTE.
The aim of this study is to derive a predictive score combining clinical and biochemical variable that predict VTE in metastatic broncho-pulmonary cancer.
详细描述
Venous thrombo-embolism (VTE) is a frequent and serious complication of cancer. However, predictive tools for VTE in cancer patients is lacking.
In patients with metastatic broncho-pulmonarycancer, biochemical characteristics might help to identify patients at high risk for VTE, particularly in adenocarcinoma.
The aim of this study is to derive a predictive score combining clinical and biochemical variable that predict VTE in metastatic broncho-pulmonary cancer.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •metastatic broncho-pulmonary cancer
- •age ≥18 years
- •who are eligible for chemotherapy
- •non opposition obtained
排除标准
- •age <18 years
- •pregnancy, breast feeding
- •VTE in the past 6 months or at the time of cancer diagnosis
- •surgery in the past 3 months
- •refusal to participate
结局指标
主要结局
venous thromboembolism at 12 months
时间窗: 12 months
objectively diagnosed VTE based on validated diagnostic tests
次要结局
- overall survival(one year)
- survival without progression(one year)
- VTE at 6 months(6 months)