NCT01037400撤回不适用
Further Development of a Biochemical Approach to Measuring Surgical Trauma to Musculoskeletal Tissues
适应症
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 试验地点
- 1
- 主要终点
- Sensitivity and Specificity of biomarkers in response to tissue injury
研究概览
简要总结
This study will examine the magnitude and time course of changes in circulating (serum and plasma) biomarker concentrations associated with musculoskeletal injury created by total knee replacement surgery. The sensitivity to injury will be characterized by the changes in mean serum concentration before and after surgery. Specificity for the injured state will be evaluated comparing the baseline to peak change (injury response) with the pre-surgery to follow-up baseline fluctuation (i.e. measurement noise).
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Sensitivity and Specificity of biomarkers in response to tissue injury
时间窗: 7 days
次要结局
未报告次要终点
研究者
Anthony Adili
Associate Professor
McMaster University
研究点 (1)
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