Prospective study of factors influencing the therapeutic failure of the surgical treatment of degenerative lumbar scoliosis

• Conditions: M41.8; Other forms of scoliosis

• Registration Number: DRKS00033358
• Lead Sponsor: Centrum für Muskuloskeletale Chirurgie, Charité - Universitätsmedizin Berlin

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2024-02-02
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 85

Inclusion Criteria

Able to consent
Diagnosis of a degenerative lumbar scoliosis with a Cobb angle of >10°
Indication for the surgical treatment with a posterior spondylodesis

Exclusion Criteria

Previous spine surgery
Spinal infection
Tumor
Contraindication for posterior spondylodesis
Necessity of additional pedicle subtraction osteotomy
Contraindication for one of the following imaging modalities: Radiographs, magnetic resonance imaging, computed imaging

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Therapeutic failure ( screw pull-out, adjacent fracture, adjacent segment degeneration) after 6 weeks, 3 months, 6 months, and 12 months

Secondary Outcome Measures

Name	Time	Method
Patient-reported outcome measures (PROMs): Oswestry Disability Index (ODI), Core Outcome Measures Index (COMI), Patient-Reported Outcomes Measurement Information System (PROMIS), Numeric Analogue Scale (NAS)