Deprescribing: a Portrait and Out-comes of the Reduction of Polypharmacy in Portugal
Trial Snapshot
- Phase
- Not Applicable
- Sponsor
- Enrollment
- 380
- Primary Endpoint
- Willingness to be deprescribed after the intervention with open-questions
Study Overview
Brief Summary
This study protocol comprises three phases. The first two phases will be nationwide and aim to evaluate the prevalence and patterns of polypharmacy and assess the barriers and facilitators of deprescribing perceived by older adults, as well as their willingness to be deprescribed and to self-medicate. The third and last phase will be a non-pharmacological randomised clinical study to measure the impact of enablement of older adults in their willingness to be deprescribed and related quality of life.
Detailed Description
Study design
This is a three-phase study:
- Cross-sectional, analytical study of the prevalence and patterns of polypharmacy, namely sociodemographic and clinical profiles (age, genre, area of residence and years of study) and about medication (number of drugs and their active component), in older adults attending Primary Care in Portugal.
- Cross-sectional, triangulation study of older adults' perception of Barriers to and Facilitators of Deprescribing, Willingness to be Deprescribed and Willingness to Self-medicate.
- Non-pharmacological randomised clinical study of the impact of enablement of older adults in their willingness to be Deprescribed and related Quality of Life.
Phase I: prevalence of polypharmacy in older adults attending primary care in Portugal Design Cross-sectional, analytical study.
Setting: Primary Care Centres in Portugal will be randomly selected from the five main-land Portuguese Healthcare Administrative Regions and two Autonomous Regions (Madeira and Azores), in order to obtain a national geographical representative sample.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Prevention
- Masking
- Double (Participant, Investigator)
Eligibility Criteria
- Ages
- 65 Years to — (Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Patients attending to the primary care consultation in the selected health centres.
Exclusion Criteria
- •Being acutely unwell in the last three weeks
- •Refuse to participate
Arms & Interventions
Elderly Enablement
The investigators will give enablement tools and talks with their GPs about how to issue the problem of polypharmacy.
Intervention: Elderly Enablement (Behavioral)
Control
This will be the control group.
Outcomes
Primary Outcomes
Willingness to be deprescribed after the intervention with open-questions
Time Frame: six months
Assess the enablement of older adults while being Deprescribed in the rise of Willingness to be Deprescribed with two open-questions (one to assess the facilitators and the other to assess the barriers) together with their perception of medication (Beliefs about Medicines Questionnaire).
Secondary Outcomes
- Quality of life after the intervention with EQ-5D(six months)
Investigators
Pedro Augusto Simões
Doctor
University of Beira Interior