aparoscopic cytoreduction After Neoadjuvant ChEmotherapy

Phase 3

Recruiting

• Conditions: Cancer of the ovaries; Epithelial ovarian cancer; 10038594; 10029903

• Registration Number: NL-OMON52155
• Lead Sponsor: Amsterdam UMC

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 15 July 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 80

Inclusion Criteria

Women with ovarian cancer who have shown good respons after three or four
courses of neoadjuvant chemotherapy. The ca 125 is normalised and on CT scan
no disease in anatomical locations that would make a laparoscopic complete
debulking not possible. They should be fit for either laparoscopic or open
surgery. In addition women with a good respons but with a ca 125 that is not
normalised can be included after a laparoscopic evaluation at the start of
surgery.

Exclusion Criteria

Intraabdominal disease that would preclude a complete debulking. Not fit for
laparoscopic surgery or laparotomy.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Disease free survival</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Health related quality of life<br /><br>Optimal cytoreduction<br /><br>Complete cytoreduction<br /><br>Overall survival<br /><br>Surgery related morbidity and mortality<br /><br>Intraoperative complications and injuries<br /><br>Conversion rate to laparotomy</p><br>