Comparison of characteristics of two drugs namely, CLONIDINE and FENTANYL as adjuncts to hyperbaric BUPIVACAINE, a drug commonly used for spinal anaesthesia in caesarean sectio
Not Applicable
- Conditions
- Health Condition 1: O998- Other specified diseases and conditions complicating pregnancy, childbirth and the puerperiumHealth Condition 2: O998- Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
- Registration Number
- CTRI/2021/09/036556
- Lead Sponsor
- nazareth hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Patients with singleton pregnancy, belonging to ASA grade I and II
2. Patients posted for elective and emergency LSCS
Exclusion Criteria
1.Patients with major neurological, cardiovascular, respiratory, renal, coagulation disorders
2.Patients with known hypersensitivity to local anaesthetics or study drugs.
3.Patients with local infection/spine deformity
4.Patients who refuse to give consent.
5.Patients whose height an weight cannot be measured before the surgery
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To evaluate block characteristics of Intrathecal CLONIDINE versus FENTANYL as adjuncts to BUPIVACAINE in caesarean sectionTimepoint: 1 year
- Secondary Outcome Measures
Name Time Method to compare the levels of sedation and associated side effects with the 2 test drugsTimepoint: 1 year
Related Research Topics
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What molecular mechanisms underlie clonidine and fentanyl's effects when combined with hyperbaric bupivacaine for spinal anesthesia in cesarean sections?
How does the comparative efficacy of clonidine versus fentanyl as adjuvants to hyperbaric bupivacaine impact block duration and quality in lower segment cesarean sections?
Which biomarkers predict optimal patient response to clonidine or fentanyl as spinal anesthesia adjuvants in O998-related obstetric complications?
What are the safety profiles and adverse event management strategies for clonidine and fentanyl in hyperbaric bupivacaine spinal anesthesia for cesarean delivery?
What alternative adjuvant drugs or combinations to clonidine/fentanyl with hyperbaric bupivacaine are being explored for spinal anesthesia in cesarean sections by Nazareth Hospital?