NL-OMON49956已完成不适用
FiberKinetics2 study: A feasibility study on fiber fermentation, and short chain fatty acid kinetics and utilization inside the gut and systemic circulation - FiberKinetics2
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 10
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •* Age 18-60yrs
- •* BMI between 18.5 and 30 kg/m2
- •* Regular bowel movement (defaecation on average once a day)
- •* Signed informed consent
排除标准
- •* Having a history of medical or surgical events that, in the opinion of the
- •Investigator, may either put the subject at risk because of participation in
- •the study, or influence the results of the study (e.g. diabetes, cardiovascular
- •disease, gastrointestinal disease, renal failure, cancer, infectious disease,
- •nose/throat).
- •* Having a history of surgical events of the gastro-intestinal tract (e.g.
- •bariatric surgery/gastric bypass surgery)
- •* Presence of swallowing disorder
- •* Use of any prescribed or non-prescribed medication (other than paracetamol)
- •including antacids, analgesics, and herbal remedies during the three (3) weeks
- •prior to study start.
- •* Being lactose intolerant
- •* Follows a vegan diet
- •* Use of antibiotics within 3 months of starting the study or planned during
- •* Use of pro- or prebiotics (e.g. galacto-oligosaccharides,
- •fructo-oligosaccharides)
- •* Constipation/infrequent bowel movement (less than 3 times defaecation per
- •* Abuse of drugs/alcohol (alcohol: >4 consumptions/day or >21 consumptions/week)
- •* Having diarrhoea within 1 month prior to the study start
- •* Personnel of Wageningen University, Division of Human Nutrition, their
- •partner and their first and second degree relatives
- •* Participation in another biomedical study or other research from the Division
- •of Human Nutrition
- •* Not willing to be exposed to fluoroscopy
- •* Is sensitive for iodinated components
- •* Having a hemoglobin of <8.5 mmol/L
- •* Having blood vessels that are too difficult for inserting a cannula
- •* Not having a general practitioner
研究者
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