Methadone induction in primary care

Phase 3

Completed

Conditions: Opioid dependence
Mental and Behavioural Disorders
Mental and behavioural disorders due to use of opioids

Registration Number: ISRCTN31125511

Lead Sponsor: ANRS - French Aids Research Agency [Agence Nationale de Recherche sur le Sida] (France)

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: All

Target Recruitment: 197

Inclusion Criteria

1. Between 18 and 70 years old
2. Opioid dependent and with an indication for methadone treatment
3. Being naive or without any previous methadone treatment during the last 30 days or having failed with buprenorphine treatment

Exclusion Criteria

1. Contraindication to methadone treatment
2. Co-dependence on alcohol and benzodiazepines
3. Inmates
4. Pregnant women
5. Individual in irregular situation or who cannot be joined by phone

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. Daily opioid use<br>2. Method of measurement: Opiate Treatment Index (OTI) - a multi-dimensional questionnaire based in patients? self-report (REF OTI- Darke et al, 1992) 12 months after enrolment (visit M12)<br>3. Prevalence (%) of opioid users at M12

Secondary Outcome Measures

Name	Time	Method
1. The prevalence of other hepatitis C virus (HCV) risk transmission practices is being documented using a series of questions extracted from a standardized questionnaire specific for this purpose, the BBV-TRAQ (Fry and Lintzeris, 2003; Tucker et al, 2004) at M12<br>2. Other indicators relevant for the purpose of this thesis are being collected: <br>2.1. Depressive symptoms Beck?s H questionnaire (Beck et al, 1985)<br>2.2. Alcohol consumption with the AUDIT questionnaire (Saunders et al, 1993)<br>2.3. Patient-health care provider relationship (Smith et al, 2006)<br>2.4. Adherence to methadone<br>2.5. Urinary drug screening and socio-demographic information on history of incarceration and contact with associations