Comparison of Gastric Residual Volume after Ingestion of Carbohydrate Drink and Water in Obese Volunteers
Phase 1
Completed
- Conditions
- Gastric Residual Volume after Ingestion of Carbohydrate Drink and Water in Obese Volunteers with Age 18 - 65 years old and body mass index greater than 29 kg/m2Gastric Residual Volume, obesity, Carbohydrate drink
- Registration Number
- TCTR20231019004
- Lead Sponsor
- Faculty of Medicine, Prince of Songkla University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
Healthy volunteers,Age 18 - 65 years old,BMI > 29 kg/m2,NPO at least 6 hours before the study
Exclusion Criteria
Diabetes Mellitus,Chronic kidney disease or End-stage renal disease, Use of any medication that affects gastric secretion or emptying (Histamine 2 receptor antagonist eg. Ranitidine/Proton pump inhibitor eg. Omeprazole/Acid neutralization eg. Aluminium hydroxide/Prokinetic eg. Domperidone) within the past 24 hours, Gastroesophageal reflux disease, Pregnancy,History of upper gastrointestinal surgery, In diet program or use appetite suppressant drug(eg. Liraglutide, Naltrexone, Phentermine, Diethylpropion) within the past 24 hours
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Gastric residual volume before intake Gastric ultrasound,Gastric residual volume immediately post-intake, Gastric ultrasound,Gastric residual volume 30 minutes post-intake Gastric ultrasound,Gastric residual volume 60 minutes post-intake Gastric ultrasound,Gastric residual volume 90 minutes post-intake Gastric ultrasound,Gastric residual volume 120 minutes post-intake Gastric ultrasound
- Secondary Outcome Measures
Name Time Method Time to empty gastric antrum - calculated from primary outcome,blood glucose levels before intake Point-of-care testing,blood glucose levels 120 minutes post-intake Point-of-care testing,hunger and thirst before intake visual analog scale,hunger and thirst 120 minutes post-intake visual analog scale