A clinical trial to study the effects of two drugs Medohar Guggulu and Weight Go in patients with obesity.

Phase 2/3

Not yet recruiting

• Conditions: Obesity, unspecified. Ayurveda Condition: MEDOROGAH,

• Registration Number: CTRI/2023/10/058244
• Lead Sponsor: Patanjali Bhartiya Ayurvigyan Evam Anusandhan Sansthan

Brief Summary

Thisstudy is a open label, double arm  comparative study, comparing the efficacy ofMedohar Guggulu each 500mg 2 tab twice daily after meal and Weight go each 640mg 2 tab daily after meal  in 40 patients with sthaulya rogathat will be conducted in Opd no. 13/14 in Patanjali ayurvedic hospital,Haridwar. Assessment will be done on the basis of subjective and objective parameter.

Route of administration- Oral route

Follow up- Follow up will be done to observe effects  of treatment or any adverse effect on the patient.

1st follow up- 1 month after commencement of treatment

2nd follow up- 1 month after the 1st follow up.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2023-03-10
• Study Start: 2023-10-14

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• Inclusion criteria Patients between the age group of 18-60 years will be selected.
• Patients having classical sign and symptoms of Sthaulya.
• Patients of either gender will be selected.
• Patients between BMI of 25-40 kg/m2 will be selected.

Exclusion Criteria

• Exclusion criteria Drug induced obesity.
• Patients having serious diseases such as hepatic disease, cardiac disease, renal disease, pulmonary disease, history of thyroid , uncontrolled hypertension and Diabetes mellitus, other endocrine disorders will be excluded.
• Other systemic diseases which intervenes with the course of treatment.
• Patients having BMI > 40kg/m2 will be excluded.
• Pregnant females and lactating women will be excluded.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Subjective parameters-Grading will be done considering sign and symptoms of sthaulya-	0day 30days 60 days
1. Sphig chalatva (Pendlous movement of buttocks)	0day 30days 60 days
2. Udara chalatva (Pendulous movement of belly)	0day 30days 60 days
3. Stana chalatva (Pendulous movement of breast)	0day 30days 60 days
4. Swasa kasta (Breathlessness)	0day 30days 60 days
5. Janusandhishoola (Pain in both knee joints)	0day 30days 60 days
6. Atinidra (Excessive sleep)	0day 30days 60 days
7. Kshudaatimatram (Increased hunger)	0day 30days 60 days
8. Pipasaatiyogam (Excessive thirst)	0day 30days 60 days
9. Swedabadha (Excessive sweating)	0day 30days 60 days
10. Daurgandhya (Foul smell from body)	0day 30days 60 days
11. Daurbalya (Weakness)	0day 30days 60 days
Objective parameter-	0day 30days 60 days
1. Body weight	0day 30days 60 days
2. Body Mass Index	0day 30days 60 days
3. Waist-Hip ratio	0day 30days 60 days
4. Measurement of circumference: Chest,abdomen,hip	0day 30days 60 days
is assessed	0day 30days 60 days

Secondary Outcome Measures

Name	Time	Method
Objective parameter-	1. Body weight

Trial Locations

Locations (1)

Patanjali Ayurveda Hospital; 🇮🇳 Hardwar, UTTARANCHAL, India

Patanjali Ayurveda Hospital

🇮🇳Hardwar, UTTARANCHAL, India

Dr Vandana

Principal investigator

6284570940

vandana35112@gmail.com