ISRCTN80832026
Completed
Not Applicable
eoadjuvant chemoradiation followed by surgery versus surgery alone for patients with adenocarcinomas or squamous cell carcinomas of the esophagus
Erasmus Medical Center, Department of Medical Oncology (Netherlands)0 sites350 target enrollmentJanuary 27, 2006
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Erasmus Medical Center, Department of Medical Oncology (Netherlands)
- Enrollment
- 350
- Status
- Completed
- Last Updated
- 11 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Age \>18, \<75 years
- •2\. Surgical resectable T2\-3, N0\-1, M0
- •3\. Tumour length longitudinal \<8 cm and radial \<5 cm
- •4\. No invasion tracheobronchial tree
- •5\. Tumour must not extend more than 2 cm into the stomach
- •6\. ECOG 0\-2
Exclusion Criteria
- •3\. Past or current history of malignancy other than entry diagnosis
- •4\. Previous chemotherapy or radiotherapy
- •5\. MI in last 6 months
- •6\. Congestive heart failure or arrhythmia requiring medication
- •7\. Neurotoxicity grade \>1
- •8\. Inadequate caloric and or fluid intake
- •9\. Weight loss 10%
Outcomes
Primary Outcomes
Not specified
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