Comparison Between spIgE and Skin Prick Test of Local and Imported Aeroallergens
- Conditions
- Immediate Hypersensitivity
- Interventions
- Procedure: Skin prick testOther: specific IgE measurement
- Registration Number
- NCT02561390
- Lead Sponsor
- Mahidol University
- Brief Summary
The prevalence of Allergic rhinitis(AR) and asthma was increased world wide. In 1998, ISAAC found that prevalence of AR and asthma inThailand was in moderately high group.
Tests for immediated reaction SPT and spIgE, were used for evaluated sensitization of allergen in patient. They guided the investigators for proper management as well as patient education. Clinician will use the result for choose allergen in case that might need immunotherapy.
SPT is safe and more economic for patient. Specific IgE has an advantage in patient who cannot withhold antihistamine prior SPT. In United state had a trial of result between SPT and spIgE for cockroach, cat, house dust mite and mold. It showed the correlation between two tests. In Thailand, the investigators haven't had data about it yet.
- Detailed Description
SPT and specific IgE for allergens is necessary for allergen avoidance and specific immunotherapy. To have local allergen extracts will help the patients to easier get the appropriate management
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 84
- Patient with controlled Asthma and/or AR (mild to moderate severity) who were diagnosed in Allergy clinic and ENT clinic, Siriraj hospital
- SPT positve one of American Cockroach, House dust mite, cat, dog and mold.
- Patient were consented to trial.
- Chronic disease such as heart disease, liver, renal and severe sepsis
- History of anaphylaxis
- Skin rash
- Pregnancy
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Skin prick test with aeroallergens Skin prick test Mean wheal diameters of SPT with commercial and local American coakroach, house dust mite, cat, dog and mold specific IgE measurement Skin prick test specific IgE levels of commercial and local American coakroach, house dust mite, cat, dog and mold Skin prick test with aeroallergens specific IgE measurement Mean wheal diameters of SPT with commercial and local American coakroach, house dust mite, cat, dog and mold specific IgE measurement specific IgE measurement specific IgE levels of commercial and local American coakroach, house dust mite, cat, dog and mold
- Primary Outcome Measures
Name Time Method mean wheal diameter of SPT of local and imported allergen extracts and specific IgE levels 18 months measure and compare SPT result of local and imported allergen extracts
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Faculty of Medicine Siriraj Hospital
🇹ðŸ‡Bangkoknoi, Bangkok, Thailand