Procalcitonin as parameter for neonatal infectio

Completed

• Conditions: infection of the newborn; Perinatal infection; 10004018

• Registration Number: NL-OMON49787
• Lead Sponsor: Spaarne Gasthuis

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 180

Inclusion Criteria

• Amenorrhea of >= 32 weeks, age <7 days old
- Neonates that had one or more prenatal risk factors for neonatal infection
according to table 2b in the NVK early-onset neonatal infection protocol, OR
neonates that are admitted with a suspected infection <7 days postpartum.

Exclusion Criteria

• (Suspected) chromosomal abnormalities or severe congenital anomalies.
• Neonates born in an other hospital/neonates who have been admitted to another
hospital in the past.

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The sensitivity and specificity of PCT for infection in the newborn tested in<br /><br>the umbilical cord blood, and in subsequent follow-up measurements in venous<br /><br>blood.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>- The level of PCT measured in umbilical cord blood.<br /><br>- The level of PCT and CRP in the blood measured in newborns with a (suspected)<br /><br>infection.</p><br>