NCT02890680CompletedNot Applicable
Randomized Double Blind Clinical Trial Evaluation of Bone Regeneration After Impacted Third Molar Surgery With the of Platelet-rich Fibrin: Pilot Study
Rio de Janeiro State University2 sites in 1 country20 target enrollmentStarted: August 1, 2016Last updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 20
- Locations
- 2
- Primary Endpoint
- Change in bone density through tomography evaluation
Study Overview
Brief Summary
The purpose of this study is to evaluate the bone regeneration after impacted third molar surgery on split mouth design using platelet-rich fibrin.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- Triple (Participant, Investigator, Outcomes Assessor)
Eligibility Criteria
- Ages
- 16 Years to 29 Years (Child, Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Healthy patients
- •Preoperative platelet count higher than 150,00/ mm3
- •Patient who required bilateral mandibular third molar extractions
Exclusion Criteria
- •Smokers patients
- •Alcoholics patients
- •Patients whom the inferior second molar was missing
- •Patients who had acute pericoronitis on the inferior third molar
- •Severe periodontal disease
Outcomes
Primary Outcomes
Change in bone density through tomography evaluation
Time Frame: Change from Baseline bone measurement at three months after surgery
Secondary Outcomes
- Change in periodontal-probing depth measurement on distal aspect of the second molar through Clinical evaluation(Change from baseline at 3 months after surgery)
- Pain through Visual Analogue Scale(7th day after surgery)
- Soft tissue healing through Clinical evaluation numeric scale(7th day after surgery)
Investigators
João Vitor dos Santos Canellas, DDS MS
MSc
Rio de Janeiro State University
Study Sites (2)
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