The Effect of Hibiscus Sabdariffa L. Tea on Blood Pressure
Phase 1
Completed
- Conditions
- Hypertension
- Registration Number
- NCT00175110
- Lead Sponsor
- Tufts University
- Brief Summary
The goal of this study is to find out whether the plant compounds present in Hibiscus sabdariffa, a plant commonly used in herbal tea blends and other beverages, will have a beneficial effect on blood pressure in people with mildly elevated blood pressure.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 66
Inclusion Criteria
- Systolic blood pressure 120-150 mm Hg
- Diastolic blood pressure 95 mm Hg or less
- Body mass index (BMI) 18.5-34.9 kg/m2
Exclusion Criteria
- Smoking
- Use of medications that influence blood pressure
- Cardiovascular disease
- Chronic kidney disease
- Diabetes
- Regular use of vitamin C supplements (min 500 mg/day) within prior 30 days
- Regular strenuous aerobic activity greater than 30 min/day
- Excessive intake of caffeine or alcohol
- Pregnancy within last 6 months or during study period
- Abnormal complete blood count (CBC), urinalysis or electrocardiogram (EKG)
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms of Hibiscus sabdariffa L. contribute to blood pressure regulation in prehypertensive and mildly hypertensive individuals?
How does Hibiscus sabdariffa L. tea compare to standard antihypertensive drug classes like ACE inhibitors and calcium channel blockers in efficacy and safety profiles?
Are there specific biomarkers or genetic factors that predict individual response to Hibiscus sabdariffa L. tisane in the context of hypertension management?
What are the known or potential adverse events associated with Hibiscus sabdariffa L. tea consumption in prehypertensive and mildly hypertensive populations, and how can they be managed?
What related compounds or combination therapies with Hibiscus sabdariffa L. have shown promise in preclinical or clinical studies for hypertension treatment?
Trial Locations
- Locations (1)
Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University
🇺🇸Boston, Massachusetts, United States
Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University🇺🇸Boston, Massachusetts, United States