Evaluation of Serratus Posterior Superior (SPS) Block Versus Surgical Intercostal Blockade in Preventing Chronic Post-Thoracotomy Pain After Video-Assisted Thoracoscopic Surgery (VATS): A Randomized, Prospective, Comparative Study.
Overview
- Phase
- Not Applicable
- Status
- Recruiting
- Sponsor
- Medipol University
- Enrollment
- 40
- Locations
- 1
- Primary Endpoint
- Incidence and severity of Chronic Post-Thoracotomy Pain (CPTP)
Overview
Brief Summary
This study aims to evaluate the efficacy of ultrasound-guided Serratus Posterior Superior (SPS) block compared to surgeon-administered intercostal blockade in preventing chronic pain at 3, 6, and 12 months following Video-Assisted Thoracoscopic Surgery (VATS).
Detailed Description
Although VATS is a minimally invasive technique, chronic post-thoracotomy pain (CPTP) remains a significant complication due to intercostal nerve injury. This study investigates whether the preemptive analgesic effect of the SPS block, performed under ultrasound guidance before surgery, reduces the incidence and severity of chronic pain more effectively than standard surgical intercostal blocks. Secondary objectives include assessing acute pain scores (VAS/NRS) within the first 24 hours, total opioid consumption, and duration of hospital stay.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- Single (Participant)
Masking Description
The patients will be blind to the study groups.
Eligibility Criteria
- Ages
- 18 Years to 75 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •ASA physical status I-III.
- •Scheduled for elective unilateral Video-Assisted Thoracoscopic Surgery (VATS).
Exclusion Criteria
- •History of allergy to local anesthetics.
- •Pre-existing chronic pain syndrome or neuropathic pain.
- •Psychiatric disorders affecting pain assessment.
- •Coagulation disorders.
- •Previous thoracic surgery on the same side.
Arms & Interventions
SPS Block Group
SPS Block will be performed at the end of the surgery
Intervention: SPS block (Drug)
Surgical Intercostal Blockade Group
Surgical Intercostal Blockade will be performed at the end of the surgery by the surgeon
Intervention: Surgical Intercostal Blockade. (Drug)
Outcomes
Primary Outcomes
Incidence and severity of Chronic Post-Thoracotomy Pain (CPTP)
Time Frame: Incidence and severity of Chronic Post-Thoracotomy Pain (CPTP) at 3, 6, and 12 months post-surgery.
The primary aim is to compare incidence and severity of Chronic Post-Thoracotomy Pain with McGill Pain Questionnaire (MPQ).
Secondary Outcomes
- Opioid consumption (Fentanyl PCA)(Changes from baseline opioid consumption at postoperative 1, 2, 4, 8, 16 and 24 hours.)
- Pain scores (Numerical rating scale-NRS)(Changes from baseline pain scores at postoperative 1, 2, 4, 8, 16 and 24 hours)
- Need for rescue analgesia (meperidine)(Postoperative 24 hours period)
- Adverse events(Postoperative 24 hours period)
- Incidence and severity of Chronic Post-Thoracotomy Pain (CPTP)(Incidence and severity of Chronic Post-Thoracotomy Pain (CPTP) at 3, 6, and 12 months post-surgery.)
Investigators
Bahadir Ciftci
Principal Investigator
Medipol University