Multimedia Aid for Genetic Testing in Gynecologic Oncology

Not Applicable

Recruiting

• Conditions: Ovary Cancer; Endometrial Cancer

• Registration Number: NCT07084168
• Lead Sponsor: UNC Lineberger Comprehensive Cancer Center

Brief Summary

This pilot study aims to estimate rates of genetic testing in patients with ovarian and endometrial cancer before and after the implementation of educational videos about genetic testing. Subjects will be asked to view one of three videos relevant to their cancer diagnosis and genetic testing, and have the option to complete a brief satisfaction survey. A chart review to evaluate rates of genetic testing ordered and referrals placed to Genetics before and after the implementation of the videos will be conducted.

Up to 15-20% of ovarian cancer and 3-5% of endometrial cancer is due to inherited genetic mutation. Given this association, the National Comprehensive Cancer Network (NCCN) recommends genetic counseling and testing for all individuals with a diagnosis of ovarian cancer and endometrial cancer. Some challenges to obtaining genetic counseling and testing include missed identification and referral of eligible patients by providers, lack of provider knowledge, and busy clinic visits limiting time for informed consent and maintaining patient autonomy for genetic testing. Although heterogeneous, the literature supports multimedia use in cancer genetics. However, there is a paucity of data in the field of gynecologic oncology for the role of integrating a multimedia approach to genetic counseling.

Detailed Description

Not available

Study Timeline

• Study Start: 2024-10-10
• Study First Submitted: 2025-07-16
• Study First Submitted QC: 2025-07-16
• Study First Posted: 2025-07-24
• Status Verified: 2025-09
• Last Update Submitted: 2025-09-03
• Last Update Posted: 2025-09-05
• Primary Completion: 2025-10-10
• Study Completion: 2025-10-10

Recruitment & Eligibility

• Status: RECRUITING
• Sex: Female
• Target Recruitment: 30

Inclusion Criteria

In order to participate in this study, a subject must meet all of the eligibility criteria outlined below.

• Reviewed informed consent to participate in the study.
• Subject is willing and able to comply with study procedures based on the judgment of the investigator.
• Age ≥ 18 years at the time of consent.
• Diagnosis of ovarian cancer or endometrial cancer
• Eligible for genetic testing
• English or Spanish is the primary language

Exclusion Criteria

• Previously completed genetic testing
• Did not receive initial cancer-directed treatment at study site

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Proportion of genetic testing	Baseline	Proportion of eligible patients undergoing any genetic testing before and after the implementation of educational videos.

Secondary Outcome Measures

Name	Time	Method
Overall rates of genetic testing	Baseline	Overall rates of genetic testing before and after the implementation of multimedia videos for patient education.
Patient satisfaction	Baseline	Total scores on patient satisfaction will be measured by a survey. Items are rated by patients on a Likert scale from 1 to 5. Higher scores represent better satisfaction.

Trial Locations

Locations (1)

Univeristy of North Carolina at Chapel Hill; 🇺🇸 Chapel Hill, North Carolina, United States