The research of the biomechanical mechanism of the combination of manipulation and exercise in the management of knee osteoarthritis based o
- Conditions
- Knee Osteoarthritis
- Registration Number
- ITMCTR2100004464
- Lead Sponsor
- Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- Not specified
1. It is in line with the KOA diagnostic standard of the medial single room in the osteoarthritis diagnosis and treatment guide (2018 edition) of the Joint Surgery Group of the Chinese Medical Association Osteology Branch;
2. The K-L grade of knee joint X-ray film was evaluated as grade 0, grade I, grade II or grade III;
3. Men or women aged 40 to 70 years;
4. Complete walking for at least 10min minutes without assistive devices;
5. High school and above culture, can correctly understand the requirements of researchers;
6. Agree to the informed consent and sign the informed consent.
1. Joint deformity, with serious complications affecting knee joint function;
2. Complicated with serious cardiovascular and cerebrovascular diseases, digestive system diseases, autoimmune diseases, psychosis, acute or chronic infection, or suffering from other neuromuscular diseases affecting gait;
3. Pregnant and lactating women;
4. Patients who had received other treatment in the last 2 months had an impact study;
5. Other situations in which the researchers considered it inappropriate to participate in the study.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Knee joint WORMS score;WOMAC scale;T2 value of cartilage of knee joint;
- Secondary Outcome Measures
Name Time Method muscle co-conrtaction;kinetics data of the knee;Force Line of knee joint;kinematics data of the knee;