NCT04649138已完成不适用
Fomepizole Dosing During Continuous Renal Replacement Therapy (CRRT)
Oslo University Hospital1 个研究点 分布在 1 个国家目标入组 11 人开始时间: 2019年6月13日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 11
- 试验地点
- 1
- 主要终点
- Measure minimum plasma concentration of fomepizole
研究概览
简要总结
The project is a prospective observation study of patients with suspected or confirmed toxic alcohol poisoning treated with fomepizole and continuous renal replacement therapy (CRRT)
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients (over 18 year) with suspected or confirmed toxic alcohol poisoning treated with fomepizole and CRRT.
排除标准
- •Patients who wish to withdraw from the study
结局指标
主要结局
Measure minimum plasma concentration of fomepizole
时间窗: through study completion, up to 72 hours
Plasma samples will be obtained up to every hour and before fomepizole is given
次要结局
- Continuous renal replacement therapy (CRRT) clearance of fomepizole(through study completion, up to 72 hours)
- Determine saturation/sieving coefficient of fomepizole(through study completion, up to 72 hours)
研究者
Knut Erik Hovda, MD, PhD
Principal Investigator
Oslo University Hospital
研究点 (1)
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