THE EFFECT OF VAGUS NERVE STIMULATION ON PRO-AND ANTI-INFLAMMATORY CYTOKINES IN PATIENTS WITH REFRACTORY EPILEPSY - VNmood

Academisch Ziekenhuis Maastricht0 个研究点目标入组 30 人开始时间: 待定最近更新: 2024年6月18日

适应症

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•1) Evidence of a progressive cerebral lesion, degenerative disorder, malignancy or a history with malignancy in the past 5 years
•2) Unstable medical disease (i.e. cardiovascular, hepatic, renal, gynaecologic, musculoskeletal, gastrointestinal, metabolic, endocrine) in the last 2 years
•3) Documented history with generalized status epilepticus in the past three months
•4) High risks for complications (obstructive respiratory disease, gastric disorders, cardiac rythm disorders)
•5) A history of alcohol or drug abuse, of psychiatric disorder requiring electro-convulsive therapy, chronic use of major tranquillisers (neuroleptics, antidepressants, or MAO inhibitors) in the past 6 months
•6) Regularly treatment with antihistamines, metoclopramide or CNS-active compounds
•7) Treatment with an experimental drug during the past 30 days
•8) Subjects who are schizophrenic or have exhibited any psychotic symptomatology

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