Activation of the ileal brake- A nutritional intervention study to assess the efficacy of a starch breakdown inhibitor and a glucose uptake inhibitor present in natural plant extracts, on the oral delivery of carbohydrates to the ileum, in a group of ileostomy patients in whom it is possible to measure glucose and other types of carbohydrates from breakfast.

Plant and Food Research Ltd0 个研究点目标入组 7 人开始时间: 2014年4月9日最近更新: 2020年1月13日

试验速览

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•Patients who have undergone an end ileostomy procedure, where the large bowel has been removed but the small bowel remains healthy and intact
•Procedure conducted more than 12 months previously, and currently stable
•This may include patients with ulcerative colitis (UC)
•Male or female, aged 20-79 years
•BMI <40kg/m2
•otherwise healthy

•Patients who have undergone loop ileostomy
•Crohn’s disease; celiac disease; diabetes mellitus (T1DM or T2DM)
•Drug therapies that may alter small bowel transit, including non-steroidal inflammatory drugs (NSAIDs), antibiotics and proton pump inhibitors
•Drug therapies that may interact with Acarbose (PrandaseTM, PrecoseTM)
•Morbid obesity, BMI >40kg/m2
•Any allergy to grape

发起方

Plant and Food Research Ltd